Dr AF Arnsten on Stress Neuroscience

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1: Mao ZM, Li BM, Arnsten AF. Related Articles, Links [Roles of alpha-2 adrenoceptor in prefrontal cortical cognitive functions] Sheng Li Ke Xue Jin Zhan. 1999 Jan;30(1):17-22. Chinese. PMID: 12532843 [PubMed - in process]


2: Lidow MS, Koh PO, Arnsten AF. Related Articles, Links D1 dopamine receptors in the mouse prefrontal cortex: Immunocytochemical and cognitive neuropharmacological analyses. Synapse. 2003 Feb;47(2):101-8. PMID: 12454947 [PubMed - indexed for MEDLINE]


3: Franowicz JS, Kessler LE, Borja CM, Kobilka BK, Limbird LE, Arnsten AF. Related Articles, Links Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. J Neurosci. 2002 Oct 1;22(19):8771-7. PMID: 12351753 [PubMed - indexed for MEDLINE]


4: Franowicz JS, Arnsten AF. Related Articles, Links Actions of alpha-2 noradrenergic agonists on spatial working memory and blood pressure in rhesus monkeys appear to be mediated by the same receptor subtype. Psychopharmacology (Berl). 2002 Jul;162(3):304-12. PMID: 12122489 [PubMed - indexed for MEDLINE]


5: Arnsten AF. Related Articles, Links Modulation of prefrontal cortical-striatal circuits: relevance to therapeutic treatments for Tourette syndrome and attention-deficit hyperactivity disorder. Adv Neurol. 2001;85:333-41. Review. No abstract available. PMID: 11530441 [PubMed - indexed for MEDLINE]


6: Scahill L, Chappell PB, Kim YS, Schultz RT, Katsovich L, Shepherd E, Arnsten AF, Cohen DJ, Leckman JF. Related Articles, Links A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry. 2001 Jul;158(7):1067-74. PMID: 11431228 [PubMed - indexed for MEDLINE]


7: Birnbaum SG, Podell DM, Arnsten AF. Related Articles, Links Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats. Pharmacol Biochem Behav. 2000 Nov;67(3):397-403. PMID: 11164065 [PubMed - indexed for MEDLINE]


8: Arnsten AF. Related Articles, Links Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine alpha-1 receptor mechanisms. Prog Brain Res. 2000;126:183-92. Review. No abstract available. PMID: 11105647 [PubMed - indexed for MEDLINE]


9: Macy JD Jr, Beattie TA, Morgenstern SE, Arnsten AF. Related Articles, Links Use of guanfacine to control self-injurious behavior in two rhesus macaques (Macaca mulatta) and one baboon (Papio anubis). Comp Med. 2000 Aug;50(4):419-25. PMID: 11020162 [PubMed - indexed for MEDLINE]


10: Arnsten AF, Murphy B, Merchant K. Related Articles, Links The selective dopamine D4 receptor antagonist, PNU-101387G, prevents stress-induced cognitive deficits in monkeys. Neuropsychopharmacology. 2000 Oct;23(4):405-10. PMID: 10989267 [PubMed - indexed for MEDLINE]


11: Arnsten AF. Related Articles, Links Genetics of childhood disorders: XVIII. ADHD, Part. 2: Norepinephrine has a critical modulatory influence on prefrontal cortical function. J Am Acad Child Adolesc Psychiatry. 2000 Sep;39(9):1201-3. Review. No abstract available. PMID: 10986819 [PubMed - indexed for MEDLINE]


12: Avery RA, Franowicz JS, Studholme C, van Dyck CH, Arnsten AF. Related Articles, Links The alpha-2A-adrenoceptor agonist, guanfacine, increases regional cerebral blood flow in dorsolateral prefrontal cortex of monkeys performing a spatial working memory task. Neuropsychopharmacology. 2000 Sep;23(3):240-9. PMID: 10942848 [PubMed - indexed for MEDLINE]


13: Arnsten AF. Related Articles, Links Through the looking glass: differential noradenergic modulation of prefrontal cortical function. Neural Plast. 2000;7(1-2):133-46. Review. No abstract available. PMID: 10709220 [PubMed - indexed for MEDLINE]


14: Birnbaum S, Gobeske KT, Auerbach J, Taylor JR, Arnsten AF. Related Articles, Links A role for norepinephrine in stress-induced cognitive deficits: alpha-1-adrenoceptor mediation in the prefrontal cortex. Biol Psychiatry. 1999 Nov 1;46(9):1266-74. PMID: 10560032 [PubMed - indexed for MEDLINE]


15: Mao ZM, Arnsten AF, Li BM. Related Articles, Links Local infusion of an alpha-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys. Biol Psychiatry. 1999 Nov 1;46(9):1259-65. PMID: 10560031 [PubMed - indexed for MEDLINE]


16: Franowicz JS, Arnsten AF. Related Articles, Links Treatment with the noradrenergic alpha-2 agonist clonidine, but not diazepam, improves spatial working memory in normal young rhesus monkeys. Neuropsychopharmacology. 1999 Nov;21(5):611-21. PMID: 10516957 [PubMed - indexed for MEDLINE]


17: Taylor JR, Birnbaum S, Ubriani R, Arnsten AF. Related Articles, Links Activation of cAMP-dependent protein kinase A in prefrontal cortex impairs working memory performance. J Neurosci. 1999 Sep 15;19(18):RC23. PMID: 10479716 [PubMed - indexed for MEDLINE]


18: Arnsten AF. Related Articles, Links Development of the cerebral cortex: XIV. Stress impairs prefrontal cortical function. J Am Acad Child Adolesc Psychiatry. 1999 Feb;38(2):220-2. No abstract available. PMID: 9951224 [PubMed - indexed for MEDLINE]


19: Arnsten AF, Mathew R, Ubriani R, Taylor JR, Li BM. Related Articles, Links Alpha-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function. Biol Psychiatry. 1999 Jan 1;45(1):26-31. PMID: 9894572 [PubMed - indexed for MEDLINE]


20: Arnsten AF. Related Articles, Links The biology of being frazzled. Science. 1998 Jun 12;280(5370):1711-2. No abstract available. PMID: 9660710 [PubMed - indexed for MEDLINE]


21: Arnsten AF, Goldman-Rakic PS. Related Articles, Links Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch Gen Psychiatry. 1998 Apr;55(4):362-8. PMID: 9554432 [PubMed - indexed for MEDLINE]


22: Franowicz JS, Arnsten AF. Related Articles, Links The alpha-2a noradrenergic agonist, guanfacine, improves delayed response performance in young adult rhesus monkeys. Psychopharmacology (Berl). 1998 Mar;136(1):8-14. PMID: 9537677 [PubMed - indexed for MEDLINE]


23: Steere JC, Arnsten AF. Related Articles, Links The alpha-2A noradrenergic receptor agonist guanfacine improves visual object discrimination reversal performance in aged rhesus monkeys. Behav Neurosci. 1997 Oct;111(5):883-91. PMID: 9383511 [PubMed - indexed for MEDLINE]


24: Arnsten AF, Steere JC, Jentsch DJ, Li BM. Related Articles, Links Noradrenergic influences on prefrontal cortical cognitive function: opposing actions at postjunctional alpha 1 versus alpha 2-adrenergic receptors. Adv Pharmacol. 1998;42:764-7. No abstract available. PMID: 9328010 [PubMed - indexed for MEDLINE]


25: Cai JX, Arnsten AF. Related Articles, Links Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys. J Pharmacol Exp Ther. 1997 Oct;283(1):183-9. PMID: 9336323 [PubMed - indexed for MEDLINE]


26: Zahrt J, Taylor JR, Mathew RG, Arnsten AF. Related Articles, Links Supranormal stimulation of D1 dopamine receptors in the rodent prefrontal cortex impairs spatial working memory performance. J Neurosci. 1997 Nov 1;17(21):8528-35. PMID: 9334425 [PubMed - indexed for MEDLINE]


27: van Dyck CH, Lin CH, Robinson R, Cellar J, Smith EO, Nelson JC, Arnsten AF, Hoffer PB. Related Articles, Links The acetylcholine releaser linopirdine increases parietal regional cerebral blood flow in Alzheimer's disease. Psychopharmacology (Berl). 1997 Aug;132(3):217-26. PMID: 9292621 [PubMed - indexed for MEDLINE]


28: Arnsten AF, Jentsch JD. Related Articles, Links The alpha-1 adrenergic agonist, cirazoline, impairs spatial working memory performance in aged monkeys. Pharmacol Biochem Behav. 1997 Sep;58(1):55-9. PMID: 9264070 [PubMed - indexed for MEDLINE]


29: Murphy BL, Roth RH, Arnsten AF. Related Articles, Links Clozapine reverses the spatial working memory deficits induced by FG7142 in monkeys. Neuropsychopharmacology. 1997 Jun;16(6):433-7. PMID: 9165499 [PubMed - indexed for MEDLINE]


30: Leckman JF, Peterson BS, Anderson GM, Arnsten AF, Pauls DL, Cohen DJ. Related Articles, Links Pathogenesis of Tourette's syndrome. J Child Psychol Psychiatry. 1997 Jan;38(1):119-42. Review. PMID: 9232461 [PubMed - indexed for MEDLINE]


31: Arnsten AF. Related Articles, Links Catecholamine regulation of the prefrontal cortex. J Psychopharmacol. 1997;11(2):151-62. Review. PMID: 9208378 [PubMed - indexed for MEDLINE]


32: Arnsten AF, Lin CH, Van Dyck CH, Stanhope KJ. Related Articles, Links The effects of 5-HT3 receptor antagonists on cognitive performance in aged monkeys. Neurobiol Aging. 1997 Jan-Feb;18(1):21-8. PMID: 8983029 [PubMed - indexed for MEDLINE]


33: Murphy BL, Arnsten AF, Jentsch JD, Roth RH. Related Articles, Links Dopamine and spatial working memory in rats and monkeys: pharmacological reversal of stress-induced impairment. J Neurosci. 1996 Dec 1;16(23):7768-75. PMID: 8922432 [PubMed - indexed for MEDLINE]


34: Arnsten AF, Steere JC, Hunt RD. Related Articles, Links The contribution of alpha 2-noradrenergic mechanisms of prefrontal cortical cognitive function. Potential significance for attention-deficit hyperactivity disorder. Arch Gen Psychiatry. 1996 May;53(5):448-55. Review. PMID: 8624188 [PubMed - indexed for MEDLINE]


35: Murphy BL, Arnsten AF, Goldman-Rakic PS, Roth RH. Related Articles, Links Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1325-9. PMID: 8577763 [PubMed - indexed for MEDLINE]


36: Steere JC, Arnsten AF. Related Articles, Links Corpus callosum morphology in ADHD. Am J Psychiatry. 1995 Jul;152(7):1105-6. No abstract available. PMID: 7793463 [PubMed - indexed for MEDLINE]


37: Arnsten AF, Cai JX, Steere JC, Goldman-Rakic PS. Related Articles, Links Dopamine D2 receptor mechanisms contribute to age-related cognitive decline: the effects of quinpirole on memory and motor performance in monkeys. J Neurosci. 1995 May;15(5 Pt 1):3429-39. PMID: 7751922 [PubMed - indexed for MEDLINE]


38: Hunt RD, Arnsten AF, Asbell MD. Related Articles, Links An open trial of guanfacine in the treatment of attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 1995 Jan;34(1):50-4. PMID: 7860456 [PubMed - indexed for MEDLINE]


39: Arnsten AF, Cai JX, Murphy BL, Goldman-Rakic PS. Related Articles, Links Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology (Berl). 1994 Oct;116(2):143-51. PMID: 7862943 [PubMed - indexed for MEDLINE]


40: Arnsten AF. Related Articles, Links Catecholamine mechanisms in age-related cognitive decline. Neurobiol Aging. 1993 Nov-Dec;14(6):639-41. No abstract available. PMID: 7905190 [PubMed - indexed for MEDLINE]


41: Arnsten AF, Cai JX. Related Articles, Links Postsynaptic alpha-2 receptor stimulation improves memory in aged monkeys: indirect effects of yohimbine versus direct effects of clonidine. Neurobiol Aging. 1993 Nov-Dec;14(6):597-603. PMID: 7905189 [PubMed - indexed for MEDLINE]


42: Berridge CW, Arnsten AF, Foote SL. Related Articles, Links Noradrenergic modulation of cognitive function: clinical implications of anatomical, electrophysiological and behavioural studies in animal models. Psychol Med. 1993 Aug;23(3):557-64. Review. No abstract available. PMID: 8234565 [PubMed - indexed for MEDLINE]


43: Arnsten AF, Contant TA. Related Articles, Links Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task. Psychopharmacology (Berl). 1992;108(1-2):159-69. PMID: 1357704 [PubMed - indexed for MEDLINE]


44: Arnsten AF, Leslie FM. Related Articles, Links Behavioral and receptor binding analysis of the alpha 2-adrenergic agonist, 5-bromo-6 [2-imidazoline-2-yl amino]


quinoxaline (UK-14304): evidence for cognitive enhancement at an alpha 2-adrenoceptor subtype. Neuropharmacology. 1991 Dec;30(12A):1279-89. PMID: 1686301 [PubMed - indexed for MEDLINE]


45: Arnsten AF, Goldman-Rakic PS. Related Articles, Links Analysis of alpha-2 adrenergic agonist effects on the delayed nonmatch-to-sample performance of aged rhesus monkeys. Neurobiol Aging. 1990 Nov-Dec;11(6):583-90. PMID: 1980719 [PubMed - indexed for MEDLINE]


46: Arnsten AF, Cai JX, Goldman-Rakic PS. Related Articles, Links The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes. J Neurosci. 1988 Nov;8(11):4287-98. PMID: 2903226 [PubMed - indexed for MEDLINE]


47: Arnsten AF, Goldman-Rakic PS. Related Articles, Links Noradrenergic mechanisms in age-related cognitive decline. J Neural Transm Suppl. 1987;24:317-24. PMID: 2824692 [PubMed - indexed for MEDLINE]


48: Arnsten AF, Goldman-Rakic PS. Related Articles, Links Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates. Science. 1985 Dec 13;230(4731):1273-6. PMID: 2999977 [PubMed - indexed for MEDLINE]


49: Arnsten AF, Berridge C, Segal DS. Related Articles, Links Stress produces opioid-like effects on investigatory behavior. Pharmacol Biochem Behav. 1985 May;22(5):803-9. PMID: 4011639 [PubMed - indexed for MEDLINE]


50: Arnsten AF, Goldman-Rakic PS. Related Articles, Links Catecholamines and cognitive decline in aged nonhuman primates. Ann N Y Acad Sci. 1985;444:218-34. No abstract available. PMID: 3925850 [PubMed - indexed for MEDLINE]


51: Arnsten AF, Neville HJ, Hillyard SA, Janowsky DS, Segal DS. Related Articles, Books, LinkOut Naloxone increases electrophysiological measures of selective information processing in humans. J Neurosci. 1984 Dec;4(12):2912-9. PMID: 6502211 [PubMed - indexed for MEDLINE]


52: Arnsten AF, Goldman-Rakic PS. Related Articles, Books, LinkOut Selective prefrontal cortical projections to the region of the locus coeruleus and raphe nuclei in the rhesus monkey. Brain Res. 1984 Jul 23;306(1-2):9-18. PMID: 6466989 [PubMed - indexed for MEDLINE]


53: Arnsten AF, Segal DS, Neville HJ, Hillyard SA, Janowsky DS, Judd LL, Bloom FE. Related Articles, Books, LinkOut Naloxone augments electrophysiological signs of selective attention in man. Nature. 1983 Aug 25-31;304(5928):725-7. PMID: 6888538 [PubMed - indexed for MEDLINE]


54: Arnsten AF, Segal DS, Loughlin SE, Roberts DC. Related Articles, Books, LinkOut Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. Brain Res. 1981 Oct 19;222(2):351-63. PMID: 7284783 [PubMed - indexed for MEDLINE]


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